Sclerotherapy 101: What to Expect When Treating Spider Veins

If you’ve noticed delicate web-like veins creeping across your legs or ankles, you’re not alone—and you’re not without options. Sclerotherapy is one of the most widely used methods for treating spider veins, offering a targeted, non-surgical solution that fits neatly into most people’s routines. This guide breaks down how the process works, what you can expect before, during, and after, and why this approach is gaining traction in local medspas and vein clinics alike.

How Sclerotherapy Works on Spider Veins

Sclerotherapy is a minimally invasive procedure that uses precise injections to collapse visible veins. The process begins when a healthcare provider injects a solution—either polidocanol or sodium tetradecyl sulfate—directly into the unwanted vein. These FDA-approved sclerosants irritate the inner lining of the vessel, triggering it to seal shut and eventually be reabsorbed by the body. The result? A gradual fading of spider veins and reticular veins over several weeks.

These sclerosants are available in foam or liquid formulations, depending on the vein type and size. Foam tends to work better for larger areas, while liquid is often used on finer capillaries. Most commonly, this procedure is done on the legs and ankles, where spider veins tend to appear due to circulation and pressure issues.

Preparing for Your First Appointment

Before undergoing Sclerotherapy, patients usually consult with a vein specialist or aesthetic provider to confirm candidacy. Not everyone qualifies—pregnant individuals, those with blood clots, or certain circulation issues may be advised to wait or consider alternatives for treating varicose veins.

In the days leading up to your appointment, it’s recommended to avoid certain medications such as aspirin, ibuprofen, and specific antibiotics. These can interfere with the efficacy of the treatment or increase the likelihood of skin irritation or bruising. On the day of the session, avoid using lotions or oils on your legs and wear loose, comfortable clothing.

What Happens During the Procedure?

The procedure itself usually takes between 30 and 45 minutes and is done in-office—no anesthesia required. You’ll either lie on your back or stomach, depending on where the veins are located. Using a fine needle, your provider will inject the sclerosant solution into each targeted vein. Some patients report a mild stinging or cramping sensation during the injection, especially in larger veins, but overall discomfort is minimal.

Typically, multiple veins are treated during each session, though the number may vary based on your specific condition and the extent of visible veins. If you’re wondering how many Sclerotherapy sessions do I need, the answer varies: many people see improvement in 2–4 sessions, while others with more prominent or widespread spider veins may require additional treatments.

What to Expect After Sclerotherapy

One of the most appreciated benefits of Sclerotherapy is its minimal downtime. You’ll be encouraged to walk and resume light activities right away to promote circulation. However, post-treatment compression wear—like medical-grade stockings—is strongly recommended for several days following the procedure. These garments help reduce swelling and support the treated veins as they close.

In terms of side effects, it’s common to experience mild bruising, itching, or temporary skin discoloration at the injection site. These symptoms typically resolve on their own within a few days to weeks. Some patients may notice firmness or small lumps under the skin where veins were treated, but this is generally short-lived.

A common question we hear is: how long does it take spider veins to go away after Sclerotherapy? Most patients begin seeing fading within 3–6 weeks, though larger veins may take up to 3–4 months for full results.

Sclerotherapy vs. Natural and Surgical Alternatives

While some individuals look into treating varicose veins naturally using herbal creams, exercise, or supplements, these approaches are often limited in their effectiveness, especially for visible spider veins. Similarly, surgical options such as vein stripping or laser ablation may be more suitable for large, bulging varicose veins but are rarely necessary for smaller cosmetic concerns.

For patients specifically seeking a treatment for spider veins on legs, Sclerotherapy remains the gold standard due to its balance of effectiveness, convenience, and safety.

Cost Considerations and Insurance Coverage

The sclerotherapy injection cost typically ranges from $300 to $600 per session, depending on the provider and number of areas treated. Insurance may cover part of the cost if the procedure is deemed medically necessary—such as in cases of pain, swelling, or circulation problems—but cosmetic treatments are usually out-of-pocket.

Always consult with your provider and insurance carrier in advance to understand coverage and payment expectations.

Aftercare and Long-Term Expectations

Proper sclerotherapy for spider veins aftercare plays a key role in achieving optimal results. Avoid hot baths, saunas, and direct sunlight for at least 48 hours post-procedure, as heat and UV exposure can interfere with healing. Gentle cleansing and cool showers are fine. Avoid strenuous exercise during the first few days and be consistent with your compression garment use.

It’s important to note that while treated veins will not return, new ones can still form over time. This is especially true for individuals with underlying vein conditions, genetic predisposition, or lifestyle factors like prolonged standing or limited movement.

The Benefits and Why It’s Worth Considering

Ultimately, Sclerotherapy offers a smart, minimally disruptive option for those seeking a visible difference without surgery or extended recovery time. Its benefits include:

• High success rate for small spider veins
• Short sessions and fast return to daily activities
• Little to no scarring
• Affordable compared to surgical interventions
• Minimal discomfort and quick recovery

Whether you’re pursuing spider vein removal for cosmetic confidence or physical comfort, it offers a scientifically backed method to improve the appearance and health of your legs—one session at a time.

If you’ve been exploring options for spider vein treatment and wondering what truly delivers, understanding both the potential and limitations of sclerotherapy is key. With realistic expectations and consistent follow-through, many patients find it to be a reliable, effective step toward smoother, healthier-looking skin.

If you’re ready for change, we’re ready to help. Reach out to start your journey with support that makes a difference.